Quantifying Golgi structure using EM: combining volume-SEM and stereology for higher throughput

Image Analysis or Stereology: Which to Choose for Quantifying Fibrosis?

Stereology: a novel technique for rapid assessment of liver volume

BACKGROUND The purpose of this study was to test the stereology method using several grid sizes for measuring liver volume and to find which grid provides an accurate estimate of liver volume. MATERIALS AND METHODS Liver volume was measured by volumetry in 41 sets of liver MRI. MRI was performed before and after different weight-reducing regimens. Grids of 3, 4, 5, and 6 cm were used to measu...

Higher-throughput approaches to crystallization and crystal structure determination.

In recent times, there has been a large increase in the number of protein structures deposited in the Protein Data Bank. Structural genomics initiatives have contributed to this expansion through their focus on high-throughput structural determination. This has fuelled advances in many of the techniques in the pipeline from gene to protein to crystal to structure. These include ligation-indepen...

Combining confocal and BSE SEM imaging for bone block surfaces.

The present report presents a method for the correlation of qualitative and quantitative BSE SEM imaging with confocal scanning light microscopy (CSLM) imaging modes applied to bone samples embedded in PMMA. The SEM has a proper digital scan generator: we leave the BSE image unchanged, and match the CSLM image to it, because the CSLM scan mechanism is not digital, though the signal is digitised...

Quantifying Bimodality Part I: An Easily Implemented Method Using <em>SPSS</em>